Yakell Quiroz, PhD is the Director of the MGH Familial Dementia Neuroimaging Lab and the Multicultural Alzheimer’s Prevention Program (MAPP) and is an Associate Professor in the Departments of Psychiatry and Neurology at Harvard Medical School. Her research focuses on the study of the neural underpinnings of memory dysfunction in the preclinical stages of Alzheimer’s disease (AD). By applying her efforts to the world’s largest family with a single, early onset AD-causing mutation (E280A in PSEN1), her research has provided evidence of brain abnormalities in individuals at genetic risk for AD decades before their clinical onset.
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This funding will support ongoing study of individuals with an autosomal dominant mutation causing early onset Alzheimer's disease, research that can inform biomarker research, disease […] -
In those with autosomal dominant Alzheimer's disease, changes in category fluency correlate with changes in brain pathology. -
Longitudinal studies conducted in Colombian families with an autosomal dominant mutation causing early onset Alzheimer's disease can inform biomarker research, disease prevention, and treatment development.