John Winkelman, MD PhD is the Chief of the Sleep Disorders Clinical Research Program in the Department of Psychiatry at Mass General and Professor of Psychiatry at Harvard Medical School. Dr. Winkelman's research has primarily focused in two areas: 1) epidemiology, physiology, cardiovascular consequences and treatment of restless legs syndrome, and 2) neurobiology and treatment of insomnia.
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Outside of the benzodiazepines, there are several classes of pharmacological agents that may prove to be useful, including sedating antidepressants, dopaminergic antagonists, anticonvulsants, melatonin agonists.