Suicide Prevention Week: Highlighting Research at Mass General Psychiatry

September 7, 2022
Ruta Nonacs, MD PhD
New research focuses on improving strategies for predicting risk of suicide, advancing our understanding of suicide risk in unique populations, and designing interventions to reduce risk of self-harm.

Improving Our Ability to Predict Who is at Risk for Suicide

Most people who attempt or die by suicide have visited a healthcare provider in the months leading up to the event; however, as clinicians, our ability to accurately predict who is at risk for suicide is poor.  Using multiple sources of data, including the electronic health record, researchers at MGH hope to develop new strategies for identifying individuals at greatest risk.  

 

Developing a Clinical Tool to Predict Suicide Risk

Clinician-researchers at Massachusetts General Hospital are using big data to better identify people at risk for suicide attempts and are developing a decision-support tool for use in clinical settings.

Suicide in Children and Adolescents

According to the Centers for Disease Control, suicide is the second leading cause of death for children, adolescents, and young adults age 15-to-24-year-olds.  However, we know considerably less about suicidal thoughts and behaviors in children and adolescents compared to adults.  Given this worrisome increase in the prevalence of suicide over the last decade, the National Institute of Mental Health has identified suicide in children and adolescents as a priority for research and intervention.  

 

Toward a Better Understanding of Suicidal Thoughts and Behaviors in Children

Although preadolescent suicide deaths are rare, suicidal thoughts and behaviors occur with concerning frequency. Male individuals were at greater risk for SITBs in preadolescence relative to adolescence. Preadolescents with ADHD, depression, and multiple psychiatric comorbidities were more likely to report suicidal ideation.

Interventions to Reduce Suicidality

While we have data to support the use of interventions which reduce depressive symptoms, we lack evidence for interventions specifically targeting suicidal and self-injurious behaviors.  There has been great interest in the use of ketamine for this purpose, given its raped effects on depression and suicidal ideation.  With a grant from the American Foundation for Suicide Prevention,  Dr. Cristina Cusin will study treatment with ketamine as a means of decreasing suicide risk in patients after discharge from psychiatric hospitalization. 

 

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