New Publications from the Mass General Department of Psychiatry – September 6, 2024

The Mass General Department of Psychiatry encompasses more than 60 specialty integrated clinical and research programs.  Our wide-ranging research portfolio spans clinical and basic research covering virtually every major psychiatric disorder, as well as the psychiatric consequences of medical illness. 

These initiatives have led to notable expansions in genetics, neuroimaging and basic neuroscience, and this model of cross-talk between clinical care and science has consistently led to research advances that inform and advance clinical care.

Physical Activity and Neurocognitive Symptoms in Older Adults During COVID-19 Pandemic.

Ortiz-Acosta PK, Martínez JE, Vila-Castelar C, Fox-Fuller JT, Pluim C, Babulal GM, Ramírez-Gómez L, Munera D, Quiroz YT, Guzmán-Vélez E.  J Appl Gerontol. 2024 Sep 4:7334648241271975. 

Avoidant/Restrictive Food Intake Disorder Symptoms Are Not as Frequent as Other Eating Disorder Symptoms When Ulcerative Colitis Is in Remission.

Burton-Murray H, Kiser K, Gurung J, Williams K, Thomas JJ, Khalili H.  J Crohns Colitis. 2024 Sep 3;18(9):1510-1513. 

Novel multi-modal methodology to investigate placebo response in major depressive disorder.

Cusin C, Dillon DG, Belleau E, Normandin MD, Petibon Y, El-Fakri G, Dhaynaut M, Hooker J, Kaptchuk T, McKee M, Hayden E, Meyer A, Jahan A, Origlio J, Ang YS, Brunner D, Kang M, Long Y, Fava M, Pizzagalli DA.  J Affect Disord. 2024 Sep 2:S0165-0327(24)01460-5. 

Anxiety and Depression Associated With Increased Cardiovascular Disease Risk Through Accelerated Development of Risk Factors.

Civieri G, Abohashem S, Grewal SS, Aldosoky W, Qamar I, Hanlon E, Choi KW, Shin LM, Rosovsky RP, Bollepalli SC, Lau HC, Armoundas A, Seligowski AV, Turgeon SM, Pitman RK, Tona F, Wasfy JH, Smoller JW, Iliceto S, Goldstein J, Gebhard C, Osborne MT, Tawakol A.  JACC Adv. 2024 Aug 14;3(9):101208. 

Difficulties in Emotion Regulation in Avoidant/Restrictive Food Intake Disorder.

Stern CM, Graver H, McPherson I, Gydus J, Kambanis PE, Breithaupt L, Burton-Murray H, Zayas L, Eddy KT, Thomas JJ, Becker KR.  Int J Eat Disord. 2024 Sep 1. 

Comorbidity Profiles of Posttraumatic Stress Disorder Across the Medical Phenome.

Hicks EM, Niarchou M, Goleva S, Kabir D, Johnson J, Johnston KJA, Ciarcia J, Pathak GA, Smoller JW, Davis LK, Nievergelt CM, Koenen KC, Huckins LM, Choi KW; PGC/PsycheMERGE PTSD & Trauma EHR Working Group.  Biol Psychiatry Glob Open Sci. 2024 May 29;4(5):100337. 

Identification of State Markers in Anorexia Nervosa: Replication and Extension of Inflammation-Associated Biomarkers Using Multiplex Profiling.

Breithaupt L, Holsen LM, Ji C, Hu J, Petterway F, Rosa-Caldwell M, Nilsson IAK, Thomas JJ, Williams KA, Boutin R, Slattery M, Bulik CM, Arnold SE, Lawson EA, Misra M, Eddy KT.  Biol Psychiatry Glob Open Sci. 2024 May 8;4(5):100332. 

Trajectory of ghrelin and PYY around a test meal in males and females with avoidant/restrictive food intake disorder versus healthy controls.

Rozzell-Voss KN, Becker KR, Tabri N, Dreier MJ, Wang SB, Kuhnle M, Gydus J, Burton-Murray H, Breithaupt L, Plessow F, Franko D, Hauser K, Asanza E, Misra M, Eddy KT, Holsen L, Micali N, Thomas JJ, Lawson EA.  Psychoneuroendocrinology. 2024 Sep;167:107063. 

Cognitive Outcomes in Autosomal-Dominant Alzheimer’s Disease: A Comprehensive Review from a Colombian Kindred with the Presenilin-1 E280A Mutation.

Giudicessi A, McDowell CP, Martinez JE, Baena A, Vila-Castelar C, Norton D, Aguirre-Acevedo DC, Tirado V, Bocanegra Y, Guzman-Velez E, Lopera F, Cronin-Golomb A, Quiroz YT.  J Alzheimers Dis. 2024 Aug 30. 

Case identification and healthcare utilization in the years prior to a first mania diagnosis.

Benson NM, Yang Z, Fung V, Smoller JW, Öngür D, Hsu J.  J Affect Disord. 2024 Aug 29;365:527-533. 

Association between childhood abuse and risk of post-COVID-19 conditions: Results from three large prospective cohort studies.

Vyas CM, Wang S, Menor AM, Kubzansky LD, Slopen N, Rich-Edwards J, Chavarro JE, Kang JH, Roberts AL.  Brain Behav Immun. 2024 Aug 25:S0889-1591(24)00569-5. 

Dietary patterns, inflammatory biomarkers and cognition in older adults: An analysis of three population-based cohorts.

Ortega N, Schütte L, de Crom TOE, Voortman T, Okereke OI, Vinceti M, von Gunten A, Marques-Vidal P, Rodondi N, Chiolero A, Chocano-Bedoya PO.  Clin Nutr. 2024 Aug 24;43(10):2336-2343. 

Prevalence and correlates of irritability among U.S. adults.

Perlis RH, Uslu A, Schulman J, Himelfarb A, Gunning FM, Solomonov N, Santillana M, Baum MA, Druckman JN, Ognyanova K, Lazer D.  Neuropsychopharmacology. 2024 Aug 24. 

Transitions of care for adolescents with disorders of gut-brain interaction.

Atkins M, Huynh D, Madva EN, Kuo B, Zar-Kessler C, Burton-Murray H, Vélez C.  J Pediatr Gastroenterol Nutr. 2024 Aug 20. 

Rationale and Design for the BLOCK-SAH Study (Pterygopalatine Fossa Block as an Opioid-Sparing Treatment for Acute Headache in Aneurysmal Subarachnoid Hemorrhage): A Phase II, Multicenter, Randomized, Double-Blinded, Placebo-Controlled Clinical Trial with a Sequential Parallel Comparison Design.

Busl KM, Smith CR, Troxel AB, Fava M, Illenberger N, Pop R, Yang W, Frota LM, Gao H, Shan G, Hoh BL, Maciel CB; BLOCK-SAH Investigators.  Neurocrit Care. 2024 Aug 13. 

PheMIME: an interactive web app and knowledge base for phenome-wide, multi-institutional multimorbidity analysis.

Zhang S, Strayer N, Vessels T, Choi K, Wang GW, Li Y, Bejan CA, Hsi RS, Bick AG, Velez Edwards DR, Savona MR, Phillips EJ, Pulley JM, Self WH, Hopkins WC, Roden DM, Smoller JW, Ruderfer DM, Xu Y.  J Am Med Inform Assoc. 2024 Aug 10:ocae182. 

Maladaptive weight control and eating behaviours in female adolescents/young adults are associated with increased risk of irritable bowel syndrome in adulthood: Results from the Growing Up Today Study (GUTS).

Yang K, Kwon S, Burton-Murray H, Kuo B, Chan AT, Field AE, Staller K.  Aliment Pharmacol Ther. 2024 Aug 5. 

Low Prevalence of Reporting of Participant Race and Ethnicity in Gastroenterology Research Publications.

Burton-Murray H, Vélez C, Boyd T, Garcia-Fischer I, Paz M, Weeks I, Kiser K, Chan AT.  Clin Transl Gastroenterol. 2024 Aug 2. 

Change in Depressive Symptoms and Longitudinal Regional Amyloid Accumulation in Unimpaired Older Adults.

Munro CE, Farrell M, Hanseeuw B, Rentz DM, Buckley R, Properzi M, Yuan Z, Vannini P, Amariglio RE, Quiroz YT, Blacker D, Sperling RA, Johnson KA, Marshall GA, Gatchel JR.  JAMA Netw Open. 2024 Aug 1;7(8):e2427248. 

Efficacy of a Mobile App-Based Intervention for Young Adults With Anxiety Disorders: A Randomized Clinical Trial.

Bress JN, Falk A, Schier MM, Jaywant A, Moroney E, Dargis M, Bennett SM, Scult MA, Volpp KG, Asch DA, Balachandran M, Perlis RH, Lee FS, Gunning FM.  JAMA Netw Open. 2024 Aug 1;7(8):e2428372.