New Publications from the Mass General Department of Psychiatry – November 1, 2024

The Mass General Department of Psychiatry encompasses more than 60 specialty integrated clinical and research programs.  Our wide-ranging research portfolio spans clinical and basic research covering virtually every major psychiatric disorder, as well as the psychiatric consequences of medical illness. 

These initiatives have led to notable expansions in genetics, neuroimaging and basic neuroscience, and this model of cross-talk between clinical care and science has consistently led to research advances that inform and advance clinical care.

Treatment paradigms for treatment-resistant schizophrenia.

Lim C, Donovan AL.  Lancet Psychiatry. 2024 Jul;11(7):488-489. 

Neuropsychiatric Complications of Hypervitaminosis D: Diagnosis, Evaluation, and Treatment.

Rustad JK, Spitz AZ, Wilson BC, Felde A, Neu N, Stern TA.  Prim Care Companion CNS Disord. 2024 Jun 13;26(3):23f03680. 

EEG complexity in emotion conflict task in individuals with psychiatric disorders.

Gu C, Chou T, Widge AS, Dougherty DD.  Behav Brain Res. 2024 Jun 5;467:114997. 

Associations between behavioral and self-reported impulsivity, brain structure, and genetic influences in middle childhood.

Gilman JM, Kaur J, Tervo-Clemmens B, Potter K, Sanzo BT, Schuster RM, Bjork JM, Evins AE, Roffman JL, Lee PH.  Dev Cogn Neurosci. 2024 Jun;67:101389. 

Longitudinal changes in the PTSD symptom network following trauma-focused treatment in military populations: Identifying central symptoms and the role of military sexual trauma.

Xu B, Kim S, Blais RK, Nadel M, Cai Q, Tanev KS.  J Anxiety Disord. 2024 Jun;104:102872. 

A Welcome Focus on Psychotherapy.

Markowitz JC, Vanderkruik RC.  J Clin Psychiatry. 2024 May 23;85(2):24ed15386. 

Prospective 2-Year Course and Predictors of Outcome in Avoidant/Restrictive Food Intake Disorder.

Kambanis PE, Tabri N, McPherson I, Gydus JE, Kuhnle M, Stern CM, Asanza E, Becker KR, Breithaupt L, Freizinger M, Shrier LA, Bern EM, Eddy KT, Misra M, Micali N, Lawson EA, Thomas JJ.  J Am Acad Child Adolesc Psychiatry. 2024 May 6:S0890-8567(24)00238-7. 

Course of avoidant/restrictive food intake disorder: Emergence of overvaluation of shape/weight.

Kambanis PE, Mancuso CJ, Becker KR, Eddy KT, Thomas JJ, De Young KP.  J Eat Disord. 2024 May 3;12(1):54. 

Intranasal Oxytocin for Obesity.

Plessow F, Kerem L, Wronski ML, Asanza E, O’Donoghue ML, Stanford FC, Eddy KT, Holmes TM, Misra M, Thomas JJ, Galbiati F, Muhammed M, Sella AC, Hauser K, Smith SE, Holman K, Gydus J, Aulinas A, Vangel M, Healy B, Kheterpal A, Torriani M, Holsen LM, Bredella MA, Lawson EA.  NEJM Evid. 2024 May;3(5):EVIDoa2300349. 

A Review of Transcranial Magnetic Stimulation and Transcranial Direct Current Stimulation Combined with Medication and Psychotherapy for Depression.

Kochanowski B, Kageki-Bonnert K, Pinkerton EA, Dougherty DD, Chou T.  Harv Rev Psychiatry. 2024 May-Jun 01;32(3):77-95. 

A Low-Intensity Transcranial Focused Ultrasound Parameter Exploration Study of the Ventral Capsule/Ventral Striatum.

Chou T, Kochanowski BJ, Hayden A, Borron BM, Barbeiro MC, Xu J, Kim JW, Zhang X, Bouchard RR, Phan KL, Goodman WK, Dougherty DD.  Neuromodulation. 2024 Apr 29: S1094-7159(24)00067-9.

Acute Stress Increases Striatal Connectivity With Cortical Regions Enriched for μ and κ Opioid Receptors.

Zhukovsky P, Ironside M, Duda JM, Moser AD, Null KE, Dhaynaut M, Normandin M, Guehl NJ, El Fakhri G, Alexander M, Holsen LM, Misra M, Narendran R, Hoye JM, Morris ED, Esfand SM, Goldstein JM, Pizzagalli DA.  Biol Psychiatry. 2024 Nov 1;96(9):717-726. 

Advancing ketamine in the treatment hierarchy for refractory depression.

Nigam K, King F 4th, Espi Forcen F.  Br J Psychiatry. 2024 Oct 25:1-3. 

Talking to Your Patients About Psychedelics: Using an Informed Approach and Understanding Indications, Risks, and Benefits.

King F, Nahlawi A, Stern TA.  Prim Care Companion CNS Disord. 2024 Oct 15;26(5):24f03783. 

Information About Sexual and Gender Minority Services and Policies on US Hospital Websites.

Sandhu S, Liu M, Fok K, Kincaid JWR, Noel WC 2nd, Keuroghlian AS.  JAMA. 2024 Oct 14. 

Ketamine for refractory depression: Save the best for last?

Nigam K, King F 4th, Espi Forcen F.  J Psychopharmacol. 2024 Sep 20:2698811241282646. 

Leukocyte telomere length and memory circuitry and cognition in early aging: Impact of sex and menopausal status.

Konishi K, Jacobs EG, Aroner S, De Vivo I, Smith B, Scribner-Weiss B, Makris N, Seitz-Holland J, Remington A, Aizley H, Kubicki M, Goldstein JM.  Horm Behav. 2024 Sep;165:105631. 

Association of Lower Rostral Anterior Cingulate GABA+ and Dysregulated Cortisol Stress Response With Altered Functional Connectivity in Young Adults With Lifetime Depression: A Multimodal Imaging Investigation of Trait and State Effects.

Ironside M, Duda JM, Moser AD, Holsen LM, Zuo CS, Du F, Perlo S, Richards CE, Chen X, Nickerson LD, Null KE, Esfand SM, Alexander MM, Crowley DJ, Lauze M, Misra M, Goldstein JM, Pizzagalli DA.  Am J Psychiatry. 2024 Jul 1;181(7):639-650. 

Amyloid and tau burden relate to longitudinal changes in the performance of complex everyday activities among cognitively unimpaired older adults: results from the performance-based Harvard Automated Phone Task.

Dubbelman MA, Diez I, Gonzalez C, Amariglio RE, Becker JA, Chhatwal JP, Gatchel JR, Johnson KA, Locascio JJ, Udeogu OJ, Wang S, Papp KV, Properzi MJ, Rentz DM, Schultz AP, Sperling RA, Vannini P, Marshall GA.  Front Aging Neurosci. 2024 Jun 12;16:1420290. 

Anosognosia is associated with increased prevalence and faster development of neuropsychiatric symptoms in mild cognitive impairment.

Wang S, Mimmack K, Cacciamani F, Elnemais Fawzy M, Munro C, Gatchel J, Marshall GA, Gagliardi G, Vannini P.  Front Aging Neurosci. 2024 Mar 6;16:1335878. 

Impact of sex and reproductive status on the default mode network in early midlife: implications for aging of memory circuitry and function.

Spets DS, Cohen JE, Konishi K, Aroner S, Misra M, Lee H, Goldstein JM.  Cereb Cortex. 2024 Mar 1;34(3):bhae088. 

Longitudinal associations of apathy and regional tau in mild cognitive impairment and dementia: Findings from the Alzheimer’s Disease Neuroimaging Initiative.

Premnath PY, Locascio JJ, Mimmack KJ, Gonzalez C, Properzi MJ, Udeogu O, Rosenberg PB, Marshall GA, Gatchel JR; Alzheimer’s Disease Neuroimaging Initiative.  Alzheimers Dement (N Y). 2024 Feb 1;10(1):e12442. doi: 10.1002/trc2.12442. eCollection 2024 Jan-Mar.