The Mass General Department of Psychiatry encompasses more than 60 specialty integrated clinical and research programs. Our wide-ranging research portfolio spans clinical and basic research covering virtually every major psychiatric disorder, as well as the psychiatric consequences of medical illness.
These initiatives have led to notable expansions in genetics, neuroimaging and basic neuroscience, and this model of cross-talk between clinical care and science has consistently led to research advances that inform and advance clinical care.
Screening, Assessment, and Pharmacologic Treatment of Mild Cognitive Impairment and Early Alzheimer’s Disease: The Role for Monoclonal Antibodies.
Weinberg MS, Principe JL, Chen A, Chung SY, Arnold SE, Stern TA. Prim Care Companion CNS Disord. 2023 Nov 28;25(6):23f03544.
Posttraumatic Stress Disorder Symptoms and Cardiovascular and Brain Health in Women.
Thurston RC, Jakubowski K, Chang Y, Wu M, Barinas Mitchell E, Aizenstein H, Koenen KC, Maki PM. JAMA Netw Open. 2023 Nov 1;6(11):e2341388.
Transitions in Prescription Benzodiazepine Use and Misuse and in Substance Use Disorder Symptoms Through Age 50.
McCabe SE, Schulenberg JE, Wilens TE, Schepis TS, McCabe VV, Veliz P. Psychiatr Serv. 2023 Nov 1;74(11):1154-1162.
Recent contributions to the field of subjective cognitive decline in aging: A literature review.
Munro CE, Boyle R, Chen X, Coughlan G, Gonzalez C, Jutten RJ, Martinez J, Orlovsky I, Robinson T, Weizenbaum E, Pluim CF, Quiroz-Gaviria YT, Gatchel JR, Vannini P, Amariglio R. Alzheimers Dement (Amst). 2023 Oct 18;15(4):e12475.
Real-World Evidence on Clinical Outcomes of Commonly Used Antidepressants in Older Adults Initiating Antidepressants for Depression: A Nationwide Cohort Study in Denmark.
Ishtiak-Ahmed K, Musliner KL, Christensen KS, Mortensen EL, Nierenberg AA, Gasse C. Am J Psychiatry. 2023 Oct 18:appiajp20230356.
Treatment-resistant depression: definition, prevalence, detection, management, and investigational interventions.
McIntyre RS, Alsuwaidan M, Baune BT, Berk M, Demyttenaere K, Goldberg JF, Gorwood P, Ho R, Kasper S, Kennedy SH, Ly-Uson J, Mansur RB, McAllister-Williams RH, Murrough JW, Nemeroff CB, Nierenberg AA, Rosenblat JD, Sanacora G, Schatzberg AF, Shelton R, Stahl SM, Trivedi MH, Vieta E, Vinberg M, Williams N, Young AH, Maj M. World Psychiatry. 2023 Oct;22(3):394-412.
Tele-Neuropsychology: From Science to Policy to Practice.
Sperling SA, Acheson SK, Fox-Fuller J, Colvin MK, Harder L, Cullum CM, Randolph JJ, Carter KR, Espe-Pfeifer P, Lacritz LH, Arnett PA, Gillaspy SR. Arch Clin Neuropsychol. 2023 Sep 15:acad066.
Morphological and transcriptomic analyses of stem cell-derived cortical neurons reveal mechanisms underlying synaptic dysfunction in schizophrenia.
Kathuria A, Lopez-Lengowski K, Watmuff B, Karmacharya R. Genome Med. 2023 Jul 28;15(1):58.
Psychopharmacological Considerations for Gender-Affirming Hormone Therapy.
Kim HH, Goetz TG, Grieve V, Keuroghlian AS. Harv Rev Psychiatry. 2023 Jul-Aug 01;31(4):183-194.
On epilepsy and education: Global perspectives and knowledge of epilepsy.
Sarkis RA, Gifford A, Chemali Z. Epilepsy Behav. 2023 Jul;144:109265.
Perspectives of Young Men Who Have Sex with Men on PrEP Adherence and Peer Navigation: A Qualitative Study.
McKetchnie SM, White B, Fontenot H, Dormitzer J, Psaros C, Fitch C, O’Cleirigh C, Mayer KH, Krakower DS. Arch Sex Behav. 2023 Jul;52(5):2037-2049.
Statistical and Conceptual Considerations in Socioepigenomics Research on Childhood Adversity and Epigenetic Aging.
Dunn EC, Simpkin AJ, Walton E. JAMA Netw Open. 2023 Jun 1;6(6):e2317958. \
The organization of frontostriatal brain wiring in non-affective early psychosis compared with healthy subjects using a novel diffusion imaging fiber cluster analysis.
Levitt JJ, Zhang F, Vangel M, Nestor PG, Rathi Y, Cetin-Karayumak S, Kubicki M, Coleman MJ, Lewandowski KE, Holt DJ, Keshavan M, Bouix S, Öngür D, Breier A, Shenton ME, O’Donnell LJ. Mol Psychiatry. 2023 Jun;28(6):2301-2311.
Pharmacological treatment of bipolar disorder and risk of diabetes mellitus: A nationwide study of 30,451 patients.
Rohde C, Köhler-Forsberg O, Nierenberg AA, Østergaard SD. Bipolar Disord. 2023 Jun;25(4):323-334.
Priorities for research on neuromodulatory subcortical systems in Alzheimer’s disease: Position paper from the NSS PIA of ISTAART.
Ehrenberg AJ, Kelberman MA, Liu KY, Dahl MJ, Weinshenker D, Falgàs N, Dutt S, Mather M, Ludwig M, Betts MJ, Winer JR, Teipel S, Weigand AJ, Eschenko O, Hämmerer D, Leiman M, Counts SE, Shine JM, Robertson IH, Levey AI, Lancini E, Son G, Schneider C, Egroo MV, Liguori C, Wang Q, Vazey EM, Rodriguez-Porcel F, Haag L, Bondi MW, Vanneste S, Freeze WM, Yi YJ, Maldinov M, Gatchel J, Satpati A, Babiloni C, Kremen WS, Howard R, Jacobs HIL, Grinberg LT. Alzheimers Dement. 2023 May;19(5):2182-2196.
The occurrence of delirium diagnosis among youth hospitalizations in the United States: A Kids’ Inpatient Database analysis.
Luccarelli J, Kalluri AS, Thom RP, Hazen EP, Pinsky E, McCoy TH Jr. Acta Psychiatr Scand. 2023 May;147(5):481-492.
A physical neural mass model framework for the analysis of oscillatory generators from laminar electrophysiological recordings.
Sanchez-Todo R, Bastos AM, Lopez-Sola E, Mercadal B, Santarnecchi E, Miller EK, Deco G, Ruffini G. Neuroimage. 2023 Apr 15;270:119938.
Sleep spindles in the healthy brain from birth through 18 years.
Kwon H, Walsh KG, Berja ED, Manoach DS, Eden UT, Kramer MA, Chu CJ. Sleep. 2023 Apr 12;46(4):zsad017.
An open trial of Collaborative Problem Solving in a naturalistic outpatient setting.
Pollastri AR, Wang L, Eddy CJ, Ablon JS. Clin Child Psychol Psychiatry. 2023 Apr;28(2):512-524.
Mind body medicine: a modern bio-psycho-social model forty-five years after Engel.
Fricchione G. Biopsychosoc Med. 2023 Mar 30;17(1):12.
Optimizing transcranial magnetic stimulation for spaceflight applications.
Romanella SM, Mencarelli L, Seyedmadani K, Jillings S, Tomilovskaya E, Rukavishnikov I, Sprugnoli G, Rossi S, Wuyts FL, Santarnecchi E. NPJ Microgravity. 2023 Mar 28;9(1):26.
A systematic review of substance use screening in outpatient behavioral health settings.
Woodward D, Wilens TE, Glantz M, Rao V, Burke C, Yule AM. Addict Sci Clin Pract. 2023 Mar 26;18(1):18.
Sensitive Periods for the Effect of Child Maltreatment on Psychopathology Symptoms in Adolescence.
Dunn EC, Busso DS, Davis KA, Smith ADAC, Mitchell C, Tiemeier H, Susser ES. Complex Psychiatry. 2023 Mar 13;9(1-4):145-153.
Occurrence and Severity of Suicidal Ideation in Adults With Neurofibromatosis Participating in a Mind-Body RCT.
Lester EG, Wang KE, Blakeley JO, Vranceanu AM. Cogn Behav Neurol. 2023 Mar 1;36(1):19-27.
Transient oscillation dynamics during sleep provide a robust basis for electroencephalographic phenotyping and biomarker identification.
Stokes PA, Rath P, Possidente T, He M, Purcell S, Manoach DS, Stickgold R, Prerau MJ. Sleep. 2023 Jan 11;46(1):zsac223.
Peer Review in a General Medical Research Journal Before and During the COVID-19 Pandemic.
Perlis RH, Kendall-Taylor J, Hart K, Ganguli I, Berlin JA, Bradley SM, Haneuse S, Inouye SK, Jacobs EA, Morris A, Ogedegbe O, Perencevich E, Shulman LN, Trueger NS, Fihn SD, Rivara FP, Flanagin A. JAMA Netw Open. 2023 Jan 3;6(1):e2253296.
A systematic review of virtual reality therapies for substance use disorders: Impact on secondary treatment outcomes.
Taubin D, Berger A, Greenwald D, Greenwald H, Burke C, Gongora DS, Wilens T. Am J Addict. 2023 Jan;32(1):13-23.
Spatial Extent of Amyloid-β Levels and Associations With Tau-PET and Cognition.
Ozlen H, Pichet Binette A, Köbe T, Meyer PF, Gonneaud J, St-Onge F, Provost K, Soucy JP, Rosa-Neto P, Breitner J, Poirier J, Villeneuve S; Alzheimer’s Disease Neuroimaging Initiative, the Harvard Aging Brain Study, the Presymptomatic Evaluation of Experimental or Novel Treatments for Alzheimer Disease Research Group. JAMA Neurol. 2022 Oct 1;79(10):1025-1035.
