New Publications from the Mass General Department of Psychiatry – March 7, 2025

The Mass General Department of Psychiatry encompasses more than 60 specialty integrated clinical and research programs.  Our wide-ranging research portfolio spans clinical and basic research covering virtually every major psychiatric disorder, as well as the psychiatric consequences of medical illness. 

These initiatives have led to notable expansions in genetics, neuroimaging and basic neuroscience, and this model of cross-talk between clinical care and science has consistently led to research advances that inform and advance clinical care.

Disentangling sex differences in PTSD risk factors.

Haering S, Seligowski AV, Linnstaedt SD, Michopoulos V, House SL, Beaudoin FL, An X, Neylan TC, Clifford GD, Germine LT, Rauch SL, Haran JP, Storrow AB, Lewandowski C, Musey PI Jr, Hendry PL, Sheikh S, Jones CW, Punches BE, Swor RA, Gentile NT, Hudak LA, Pascual JL, Seamon MJ, Pearson C, Peak DA, Merchant RC, Domeier RM, Rathlev NK, O’Neil BJ, Sanchez LD, Bruce SE, Harte SE, McLean SA, Kessler RC, Koenen KC, Powers A, Stevens JS.  Nat Ment Health. 2024 May;2(5):605-615. 

Participant Experiences from a Randomized Controlled Trial of Heated Yoga for Depression.

Nyer MB, Ding GA, Norton RJ, Nagaswami MV, Tuchman S, Fisher LB, Hopkins LB, Giollabhui NM, Koontz J, Mason AE, Cusin C, Foster S, Yeung A, Jain FA, Sorensen CEC, Streeter C, Miller KK, Fava M, Uebelacker L, Mischoulon D. Int J Yoga Therap. 2024 Oct 1;34(2024):Article 11.Cite 

The Short-Term Course of Nonsuicidal Self-Injury Among Individuals Seeking Psychiatric Treatment.

Kiekens G, Claes L, Kleiman EM, Luyckx K, Coppersmith DDL, Fortgang RG, Myin-Germeys I, Nock MK.  JAMA Netw Open. 2024 Oct 1;7(10):e2440510. 

Patient and staff perspectives on pain treatment experiences in a community clinic serving under-resourced older adults.

Brewer JR, McDermott KA, Greenberg J, Presciutti AM, LaCamera DE, Ritchie CS, Vranceanu AM.  Pain Manag. 2024 Oct-Nov;14(10-11):549-556. 

What should constitute a control condition in psychedelic drug trials?

Colloca L, Fava M.  Nat Ment Health. 2024 Oct;2(10):1152-1160. 

Prior resilience to trauma & coping during the COVID-19 pandemic.

Scoglio AAJ, Nishimi K, Choi KW, Koenen KC, Sampson LA, Jha SC, Kubzansky LD. PLoS One. 2024 May 7;19(5):e0297169. 

Generalized Periodic Discharges Associated With Catatonia and Delirium: A Case Series.

Luccarelli J, Smith JR, Fricchione G, Westover MB.  J Neuropsychiatry Clin Neurosci. 2024 Fall;36(4):340-343. 

The cumulative impact of trauma, chronic illness, and COVID-19 stress on mental health in a case-control study of adults with psychotic disorders in Ethiopia.

Sharma M, Alemayehu M, Girma E, Milkias B, Stevenson A, Gelaye B, Koenen KC, Teferra S.  Compr Psychiatry. 2024 Oct;134:152508. 

Intention to quit or reduce e-cigarettes, cannabis, and their co-use among a school-based sample of adolescents.

Liu J, Knoll SJ, Pascale MP, Gray CA, Bodolay A, Potter KW, Gilman J, Eden Evins A, Schuster RM.  Addict Behav. 2024 Oct;157:108101. 

Diagnostic and demographic factors of pediatric and adult catatonia hospitalizations: A 2016-2020 National Inpatient Sample Study.

Luccarelli J, Kalinich M, Fricchione G, Smith F, Beach SR, Smith JR.  Acta Psychiatr Scand. 2024 Oct;150(4):234-244. 

Sex-dependent differences in vulnerability to early risk factors for posttraumatic stress disorder: results from the AURORA study.

Haering S, Seligowski AV, Linnstaedt SD, Michopoulos V, House SL, Beaudoin FL, An X, Neylan TC, Clifford GD, Germine LT, Rauch SL, Haran JP, Storrow AB, Lewandowski C, Musey PI Jr, Hendry PL, Sheikh S, Jones CW, Punches BE, Swor RA, Gentile NT, Hudak LA, Pascual JL, Seamon MJ, Pearson C, Peak DA, Merchant RC, Domeier RM, Rathlev NK, O’Neil BJ, Sanchez LD, Bruce SE, Harte SE, McLean SA, Kessler RC, Koenen KC, Stevens JS, Powers A.  Psychol Med. 2024 May 22:1-11. 

Systems biology dissection of PTSD and MDD across brain regions, cell types, and blood.

Daskalakis NP, Iatrou A, Chatzinakos C, Jajoo A, Snijders C, Wylie D, DiPietro CP, Tsatsani I, Chen CY, Pernia CD, Soliva-Estruch M, Arasappan D, Bharadwaj RA, Collado-Torres L, Wuchty S, Alvarez VE, Dammer EB, Deep-Soboslay A, Duong DM, Eagles N, Huber BR, Huuki L, Holstein VL, Logue MW, Lugenbühl JF, Maihofer AX, Miller MW, Nievergelt CM, Pertea G, Ross D, Sendi MSE, Sun BB, Tao R, Tooke J, Wolf EJ, Zeier Z; PTSD Working Group of Psychiatric Genomics Consortium**; Berretta S, Champagne FA, Hyde T, Seyfried NT, Shin JH, Weinberger DR, Nemeroff CB, Kleinman JE, Ressler KJ; PTSD Working Group of Psychiatric Genomics Consortium.  Science. 2024 May 24;384(6698):eadh3707. 

Cross-cultural equivalence of the Kessler Psychological Distress Scale (K10) across four African countries in a multi-national study of adults.

Ametaj AA, Denckla CA, Stevenson A, Stroud RE 2nd, Hall J, Ongeri L, Milkias B, Hoffman J, Naisanga M, Akena D, Kyebuzibwa J, Kwobah EK, Atwoli L, Gichuru S, Teferra S, Alemayehu M, Zingela Z, Stein DJ, Pretorius A, Newton CRJC, Mwema RM, Kariuki SM, Koenen KC, Gelaye B.  SSM Ment Health. 2024 Jun;5:100300. 

Intensive longitudinal assessment following index trauma to predict development of PTSD using machine learning.

Horwitz A, McCarthy K, House SL, Beaudoin FL, An X, Neylan TC, Clifford GD, Linnstaedt SD, Germine LT, Rauch SL, Haran JP, Storrow AB, Lewandowski C, Musey PI Jr, Hendry PL, Sheikh S, Jones CW, Punches BE, Swor RA, Hudak LA, Pascual JL, Seamon MJ, Harris E, Pearson C, Peak DA, Domeier RM, Rathlev NK, Sergot P, Sanchez LD, Bruce SE, Joormann J, Harte SE, Koenen KC, McLean SA, Sen S.  J Anxiety Disord. 2024 Jun;104:102876. 

The aggregation of marginal gains: a pragmatic philosophy of clinical care in psychiatry.

Berk M, Marx W, Nierenberg AA.  World Psychiatry. 2024 Jun;23(2):291-292. 

Sex Differences in Response Inhibition-Related Neural Predictors of Posttraumatic Stress Disorder in Civilians With Recent Trauma.

Borst B, Jovanovic T, House SL, Bruce SE, Harnett NG, Roeckner AR, Ely TD, Lebois LAM, Young D, Beaudoin FL, An X, Neylan TC, Clifford GD, Linnstaedt SD, Germine LT, Bollen KA, Rauch SL, Haran JP, Storrow AB, Lewandowski C, Musey PI Jr, Hendry PL, Sheikh S, Jones CW, Punches BE, Hudak LA, Pascual JL, Seamon MJ, Datner EM, Pearson C, Peak DA, Domeier RM, Rathlev NK, O’Neil BJ, Sergot P, Sanchez LD, Harte SE, Koenen KC, Kessler RC, McLean SA, Ressler KJ, Stevens JS, van Rooij SJH.  Biol Psychiatry Cogn Neurosci Neuroimaging. 2024 Jul;9(7):668-680.