New Publications from the Mass General Department of Psychiatry – March 14, 2025

The Mass General Department of Psychiatry encompasses more than 60 specialty integrated clinical and research programs.  Our wide-ranging research portfolio spans clinical and basic research covering virtually every major psychiatric disorder, as well as the psychiatric consequences of medical illness. 

These initiatives have led to notable expansions in genetics, neuroimaging and basic neuroscience, and this model of cross-talk between clinical care and science has consistently led to research advances that inform and advance clinical care.

National trends and correlates of treatment resistance in major depressive episode and associated suicidal ideation and behaviors among adults in the United States.

Rhee TG, Bommersbach TJ, Rosenheck RA, Nierenberg AA, McIntyre RS.  J Affect Disord. 2024 Aug 1;358:342-349. 

Probing the neurocardiac circuit in trauma and posttraumatic stress.

Seligowski AV, Harnett NG, Ellis RA, Grasser LR, Hanif M, Wiltshire C, Ely TD, Lebois LAM, van Rooij SJH, House SL, Beaudoin FL, An X, Neylan TC, Clifford GD, Linnstaedt SD, Germine LT, Bollen KA, Rauch SL, Haran JP, Storrow AB, Lewandowski C, Musey PI Jr, Hendry PL, Sheikh S, Jones CW, Punches BE, Swor RA, Hudak LA, Pascual JL, Seamon MJ, Harris E, Pearson C, Peak DA, Merchant RC, Domeier RM, Rathlev NK, O’Neil BJ, Sergot P, Sanchez LD, Bruce SE, Harte SE, Koenen KC, Kessler RC, McLean SA, Ressler KJ, Stevens JS, Jovanovic T.  J Psychiatr Res. 2024 Aug;176:173-181. 

Relationships between trauma types and psychotic symptoms: A network analysis of patients with psychotic disorders in a large, multi-country study in East Africa.

Stevenson A, Misra S, Girma E, Isvoranu AM, Akena D, Alemayehu M, Atwoli L, Gelaye B, Gichuru S, Kariuki SM, Kwobah EK, Kyebuzibwa J, Mwema RM, Newman CP, Newton CRJC, Ongeri L, Stroud RE 2nd, Teferra S, Koenen KC, Seedat S.  Compr Psychiatry. 2024 Aug;133:152504. 

The effectiveness of the lorazepam challenge test in pediatric catatonia: A multisite retrospective cohort study.

Luccarelli J, McCoy TH Jr, York T, Baldwin I, Fricchione G, Fuchs C, Smith JR.   Schizophr Res. 2024 Aug;270:410-415. 

Gender Representation in the ECT Workforce in the United States From 2013 to 2021: A Medicare Physician Data Analysis.

Luccarelli J, Hart KL, McCoy TH Jr.  J ECT. 2024 Aug 1:10.1097/YCT.0000000000001026. 

Assessment of suicidal thoughts and behaviors in adults: A systematic review of measure psychometric properties and implications for clinical and research utility.

Pollak OH, Sheehan AE, Walsh RFL, Stephenson AR, Zell H, Mayes J, Lawrence HR, Bettis AH, Liu RT.  Clin Psychol Rev. 2024 Aug;112:102464. 

Coping and emotion regulation: A conceptual and measurement scoping review.

Trudel-Fitzgerald C, Boucher G, Morin C, Mondragon P, Guimond AJ, Nishimi K, Choi KW, Denckla C.  Can Psychol. 2024 Aug;65(3):149-162. 

Understanding the barriers and facilitators of healthcare services for brain injury and concurrent mental health and substance use issues: a qualitative study.

Grewal J, Kennedy CJ, Mamman R, Biagioni JB, Garcia-Barrera MA, Schmidt J.  BMC Health Serv Res. 2024 Aug 2;24(1):881. 

Acceptability and Feasibility of an Ecological Momentary Intervention for Managing Emotional Distress Among Psychiatric Inpatients at Risk for Suicide.

Kleiman EM, Bentley KH, Jaroszewski AC, Maimone JS, Fortgang RG, Zuromski KL, Kilbury EN, Stein MB, Beck S, Huffman JC, Nock MK.  Arch Suicide Res. 2024 Aug 26:1-18.

Childhood maltreatment and health in the UK Biobank: triangulation of outcome-wide and polygenic risk score analyses.

Espinosa Dice AL, Lawn RB, Ratanatharathorn A, Roberts AL, Denckla CA, Kim AH, de la Rosa PA, Zhu Y, VanderWeele TJ, Koenen KC.  BMC Med. 2024 Mar 25;22(1):135. 

Effects of genetically predicted posttraumatic stress disorder on autoimmune phenotypes.

Maihofer AX, Ratanatharathorn A, Hemmings SMJ, Costenbader KH, Michopoulos V, Polimanti R, Rothbaum AO, Seedat S, Mikita EA; CHARGE Inflammation Working Group; Psychiatric Genomics Consortium PTSD Working Group; Smith AK, Salem RM, Shaffer RA, Wu T, Sebat J, Ressler KJ, Stein MB, Koenen KC, Wolf EJ, Sumner JA, Nievergelt CM.  Transl Psychiatry. 2024 Apr 1; 14(1):172. 

Posttraumatic stress disorder symptoms in systemic autoimmune rheumatic disease patients during the early COVID-19 pandemic.

Oakes EG, Ellrodt J, Yee J, Guan H, Kubzansky LD, Koenen KC, Costenbader KH.  Int J Rheum Dis. 2024 Jan;27(1):e14974. 

Psychometric Properties of the Mini International Neuropsychiatric Interview (MINI) Psychosis Module: A Sub-Saharan Africa Cross Country Comparison – CORRIGENDUM.

Korte KJ, Jaguga F, Kim HH, Stroud RE, Stevenson A, Akena D, Atwoli L, Gichuru S, James R, Kwobah E, Kariuki SM, Kyebuzibwa J, Mwema RM, Newton CRJC, Zingela Z, Stein DJ, Alemayehu M, Teferra S, Koenen KC, Gelaye B.  Psychol Med. 2024 Jan;54(2):436. 

Does baseline psychiatric symptom severity predict well-being improvement in low-intensity mindfulness interventions?

Gold AK, Rabideau DJ, Nolte D, Faria CM, Deng SY, George N, Boccagno C, Temes CM, Kamali M, Akpolat N, Nierenberg AA, Sylvia LG.  Psychiatry Res Commun. 2024 Sep;4(3):100182. 

Year-Long Cannabis Use for Medical Symptoms and Brain Activation During Cognitive Processes.

Burdinski DCL, Kodibagkar A, Potter K, Schuster RM, Evins AE, Ghosh SS, Gilman JM.

JAMA Netw Open. 2024 Sep 3;7(9):e2434354. 

Racial Differences in Nicotine Reduction: Pooled Results from Two Double-Blind Randomized Controlled Trials.

Lin W, Krebs NM, Zhu J, Horn K, Foulds J, Evins AE, Muscat JE. J Racial Ethn Health Disparities. 2024 Sep 4. 

An Examination of Sleep as a Protective Factor for Depression and Anxiety in the Perinatal Period: Novel Causal Analyses in a Prospective Pregnancy Cohort.

Basu A, Sarvet A, Chen JT, Denckla C, Zhu Y, Koenen KC.  Am J Epidemiol. 2024 Sep 11:

Further evidence that peritraumatic 17β-estradiol levels influence chronic posttraumatic pain outcomes in women, data from both humans and animals.

Son E, Gaither R, Lobo J, Zhao Y, McKibben LA, Arora R, Albertorio-Sáez L, Mickelson J, Wanstrath BJ, Bhatia S, Stevens JS, Jovanovic T, Koenen K, Kessler R, Ressler K, Beaudoin FL, McLean SA, Linnstaedt SD.  Pain. 2024 Sep 13. 

Do tobacco regulatory and economic factors influence smoking cessation outcomes? A post-hoc analysis of the multinational EAGLES randomised controlled trial.

Daniel B, Lawrence DE, McKenna BS, Saccone P, McRae T, Evins AE, Anthenelli RM.  BMJ Open. 2024 Sep 20;14(9):e079092.