The Mass General Department of Psychiatry encompasses more than 60 specialty integrated clinical and research programs. Our wide-ranging research portfolio spans clinical and basic research covering virtually every major psychiatric disorder, as well as the psychiatric consequences of medical illness.
These initiatives have led to notable expansions in genetics, neuroimaging and basic neuroscience, and this model of cross-talk between clinical care and science has consistently led to research advances that inform and advance clinical care.
Establishing the validity of a diagnostic questionnaire for childbirth-related posttraumatic stress disorder.
Arora IH, Woscoboinik GG, Mokhtar S, Quagliarini B, Bartal A, Jagodnik KM, Barry RL, Edlow AG, Orr SP, Dekel S. Am J Obstet Gynecol. 2023 Nov 21.
Nonsuicidal self-injury characteristics: A mixed methods analysis of differences between veterans and civilians.
Barnette BH, O’Loughlin CM, Park Y, Vogel K, Burke TA, Law KC, Ammerman BA. J Psychiatr Res. 2023 Dec;168:318-324.
Identifying women with postdelivery posttraumatic stress disorder using natural language processing of personal childbirth narratives.
Bartal A, Jagodnik KM, Chan SJ, Babu MS, Dekel S. Am J Obstet Gynecol MFM. 2023 Mar;5(3):100834.
Disrupted white matter integrity in primary insomnia and major depressive disorder: relationships to sleep quality and depression severity.
Benson KL, Winkelman JW, Gönenç A. J Sleep Res. 2023 Oct;32(5):e13913.
Characterizing Adolescent Disclosures of Suicidal Thoughts and Behavior to Parents.
Bettis AH, Cosby E, Benningfield MM, Fox K, Burke TA. J Adolesc Health. 2023 Sep;73(3):591-594.
Nonsuicidal Self-Injury in Preadolescents.
Burke TA, Bettis AH, Walsh RFL, Levin RY, Lawrence HR, Sheehan AE, Turnamian MR, Liu RT. Pediatrics. 2023 Dec 1;152(6).
Brain tissue iron neurophysiology and its relationship with the cognitive effects of dopaminergic modulation in children with and without ADHD.
Cascone AD, Calabro F, Foran W, Larsen B, Nugiel T, Parr AC, Tervo-Clemmens B, Luna B, Cohen JR. Dev Cogn Neurosci. 2023 Oct;63:101274.
Cognitive inflexibility and suicidal ideation among adolescents following hospitalization: The moderating role of life stress.
Cheek SM, Kudinova AY, Kuzyk EG, Goldston DB, Liu RT. J Affect Disord. 2023 Oct 15;339:698-705.
Exploring mechanisms of improvement in the Active Brains intervention for older adults with chronic pain and early cognitive decline.
Choukas NR, Mace RA, Rochon EA, Brewer JR, Vranceanu AM. Arch Gerontol Geriatr. 2023 Nov 29;118:105290.
Investigation of advanced mindfulness meditation “cessation” experiences using EEG spectral analysis in an intensively sampled case study.
Chowdhury A, van Lutterveld R, Laukkonen RE, Slagter HA, Ingram DM, Sacchet MD. Neuropsychologia. 2023 Nov 5;190:108694. doi: 10.1016/j.neuropsychologia.2023.108694. Epub 2023 Sep 28.
Preventing Post-Traumatic Stress Disorder following Childbirth: A Systematic Review and Meta-Analysis.
Dekel S, Papadakis JE, Quagliarini B, Pham CT, Pacheco-Barrios K, Hughes F, Jagodnik KM, Nandru R. Am J Obstet Gynecol. 2023 Dec 18.
Perceived discrimination and problematic opioid use among Black individuals with chronic musculoskeletal pain.
Doorley JD, Hooker JE, Briskin EA, Bakhshaie J, Vranceanu AM. Psychol Addict Behav. 2023 Dec 7.
How Do Orthopaedic Providers Conceptualize Good Patient Outcomes and Their Barriers and Facilitators After Acute Injury? A Qualitative Study.
Doorley JD, Fishbein NS, Greenberg J, Reichman M, Briskin EA, Bakhshaie J, Vranceanu AM. Clin Orthop Relat Res. 2023 Jun 1;481(6):1088-1100.
BDNF rs6265 Met carriers with alcohol use disorder show greater age-related decline of N-acetylaspartate in left dorsolateral prefrontal cortex.
Durazzo TC, McNerney MW, Hansen AM, Gu M, Sacchet MD, Padula CB. Drug Alcohol Depend. 2023 Jul 1;248:109901.
Life-Course Brain Health as a Determinant of Late-Life Mental Health: American Association for Geriatric Psychiatry Expert Panel Recommendations.
Eyre HA, Stirland LE, Jeste DV, Reynolds CF 3rd, Berk M, Ibanez A, Dawson WD, Lawlor B, Leroi I, Yaffe K, Gatchel JR, Karp JF, Newhouse P, Rosand J, Letourneau N, Bayen E, Farina F, Booi L, Devanand DP, Mintzer J, Madigan S, Jayapurwala I, et al. Am J Geriatr Psychiatry. 2023 Dec;31(12):1017-1031.
Early Alzheimer’s disease pathology in human cortex involves transient cell states.
Gazestani V, Kamath T, Nadaf NM, Dougalis A, Burris SJ, Rooney B, Junkkari A, Vanderburg C, Pelkonen A, Gomez-Budia M, Välimäki NN, Rauramaa T, Therrien M, Koivisto AM, Tegtmeyer M, Herukka SK, Abdulraouf A, Marsh SE, Hiltunen M, Nehme R, Malm T, Stevens B, et al. Cell. 2023 Sep 28;186(20):4438-4453.e23.
Another Step Toward the Prediction of Antipsychotic Treatment Response Using Functional Connectivity.
Goff DC, Roffman J, Holt DJ. Am J Psychiatry. 2023 Nov 1;180(11):787-788.
Associations of the Harvard Automated Phone Task and Alzheimer’s Disease Pathology in Cognitively Normal Older Adults: Preliminary Findings.
Gonzalez C, Mimmack KJ, Amariglio RE, Becker JA, Chhatwal JP, Fitzpatrick CD, Gatchel JR, Johnson KA, Katz ZS, Kuppe MK, Locascio JJ, Udeogu OJ, Papp KV, Premnath P, Properzi MJ, Rentz DM, Schultz AP, Sperling RA, Vannini P, Wang S, Marshall GA. J Alzheimers Dis. 2023;94(1):217-226.
Pain catastrophizing, pain anxiety, and substance use among Black individuals with chronic pain who use opioids.
Greenberg J, Penn T, Doorley JD, Grunberg VA, Duarte BA, Fishbein NS, Bakhshaie J, Vranceanu AM. Psychol Addict Behav. 2023 Nov;37(7):977-984.
Meta-Analyses of Genome-Wide Association Studies for Postpartum Depression.
Guintivano J, Byrne EM, Kiewa J, Yao S, Bauer AE, Aberg KA, Adams MJ, Campbell A, Campbell ML, Choi KW, Corfield EC, Havdahl A, Hucks D, Koen N, Lu Y, Mægbæk ML, Mullaert J, Peterson RE, Raffield LM, Sallis HM, Sealock JM, Walker A, et al. Am J Psychiatry. 2023 Dec 1;180(12):884-895.
Association of Pathologic and Volumetric Biomarker Changes With Cognitive Decline in Clinically Normal Adults.
Hanseeuw BJ, Jacobs HIL, Schultz AP, Buckley RF, Farrell ME, Guehl NJ, Becker JA, Properzi M, Sanchez JS, Quiroz YT, Vannini P, Sepulcre J, Yang HS, Chhatwal JP, Gatchel J, Marshall GA, Amariglio R, Papp K, Rentz DM, Normandin M, Price JC, Healy BC, et al. Neurology. 2023 Dec 12;101(24):e2533-e2544.
Depressive Symptoms are Associated With C-Reactive Protein in Older Adults With Obesity.
Heisey HD, Qualls C, Villareal DT, Segoviano-Escobar MB, Nava MLD, Gatchel JR, Kunik ME. J Geriatr Psychiatry Neurol. 2023 Nov 11:8919887231215041.
