New Publications from the Mass General Department of Psychiatry – April 3, 2025

The Mass General Department of Psychiatry encompasses more than 60 specialty integrated clinical and research programs.  Our wide-ranging research portfolio spans clinical and basic research covering virtually every major psychiatric disorder, as well as the psychiatric consequences of medical illness. 

These initiatives have led to notable expansions in genetics, neuroimaging and basic neuroscience, and this model of cross-talk between clinical care and science has consistently led to research advances that inform and advance clinical care.

Empirical Approaches to the Classification of Avoidant/Restrictive Food Intake Disorder.

Richson BN, Schaefer LM, Becker KR, Murray MF, Romano KA, Anderson LM, Wonderlich SA, Thomas JJ.  Int J Eat Disord. 2024 Nov 30. 

Integrative multi-omics analysis to gain new insights into COVID-19.

Eshetie S, Choi KW, Hyppönen E, Benyamin B, Lee SH.  Sci Rep. 2024 Nov 30;14(1):29803. 

EEG measures of brain arousal in relation to symptom improvement in patients with major depressive disorder: Results from a randomized placebo-controlled clinical trial.

Ulke C, Kayser J, Tenke CE, Mergl R, Sander C, Panier LY, Alvarenga JE, Fava M, McGrath PJ, Deldin PJ, McInnis MG, Trivedi MH, Weissman MM, Pizzagalli DA, Hegerl U, Bruder GE.

Psychiatry Res. 2024 Dec;342:116165. 

Using the Socioecological Model to Understand Medical Staff and Older Adult Patients’ Experience with Chronic Pain: A Qualitative Study in an Underserved Community Setting.

McDermott K, Presciutti AM, Levey N, Brewer J, Rush CL, Giraldo-Santiago N, Pham TV, Pasinski R, Yousif N, Gholston M, Raju V, Greenberg J, Ritchie CS, Vranceanu AM.  J Pain Res. 2024 Nov 19;17:3881-3895. 

Pain catastrophizing and pain anxiety mediate changes in physical function in a mind-body intervention for adults with traumatic orthopedic injuries.

Gnall KE, Jochimsen KN, Brewer JR, Bakhshaie J, Vranceanu AM.  Pain. 2024 Nov 19. 

Serious mental health conditions and exposure to adulthood trauma in low- and middle-income countries: a scoping review.

Stevenson A, Girma E, Kitafuna BK, Harerimana B, Koenen KC, Seedat S.  Glob Ment Health (Camb). 2024 Nov 20;11:e112. 

Socio-ecological barriers to behavior change-oriented dementia prevention: a qualitative study of healthcare professionals’ perspectives.

Mace RA, Cohen JE, Lyons C, Ritchie C, Bartels S, Okereke OI, Hoeppner BB, Brewer J, Joo JH, Vranceanu AM.  Aging Ment Health. 2024 Nov 22:1-10. 

Technical variability across the 450K, EPICv1, and EPICv2 DNA methylation arrays: lessons learned for clinical and longitudinal studies.

Lussier AA, Schuurmans IK, Großbach A, Maclsaac J, Dever K, Koen N, Zar HJ, Stein DJ, Kobor MS, Dunn EC.  Clin Epigenetics. 2024 Nov 22;16(1):166. 

Social Buffering of Posttraumatic Stress Disorder: Longitudinal Effects and Neural Mediators.

Santos JLC, Harnett NG, van Rooij SJH, Ely TD, Jovanovic T, Lebois LAM, Beaudoin FL, An X, Neylan TC, Linnstaedt SD, Germine LT, Bollen KA, Rauch SL, Haran JP, Storrow AB, Lewandowski C, Musey PI Jr, Hendry PL, Sheikh S, Jones CW, Punches BE, Pascual JL, Seamon MJ, Harris E, Pearson C, Peak DA, Merchant RC, Domeier RM, Rathlev NK, O’Neil BJ, Sergot P, Sanchez LD, Bruce SE, Pizzagalli DA, Harte SE, Ressler KJ, Koenen KC, McLean SA, Stevens JS.  Biol Psychiatry Cogn Neurosci Neuroimaging. 2024 Nov 26:S2451-9022(24)00348-3. 

 The efficacy of psychological treatments on body dysmorphic disorder: a meta-analysis and trial sequential analysis of randomized controlled trials.

Liu Y, Lai L, Wilhelm S, Phillips KA, Guo Y, Greenberg JL, Ren Z.  Psychol Med. 2024 Dec 3;54(15):1-14. 

Understanding the relationship between childhood abuse and affective symptoms in bipolar disorder: New insights from a network analysis.

Wrobel AL, Turner M, Dean OM, Berk M, Sylvia LG, Thase ME, Deckersbach T, Tohen M, McInnis MG, Kocsis JH, Shelton RC, Ostacher MJ, Iosifescu DV, McElroy SL, Turner A, Nierenberg AA.  Psychiatry Res. 2024 Dec;342:116197. 

ENIGMA-Chronic Pain: a worldwide initiative to identify brain correlates of chronic pain.

Quidé Y, Jahanshad N, Andoh J, Antoniou G, Apkarian AV, Ashar YK, Badran BW, Baird CL, Baxter L, Bell TR, Blanco-Hinojo L, Borckardt J, Cheung CL, Ciampi de Andrade D, Couto BA, Cox SR, Cruz-Almeida Y, Dannlowski U, De Martino E, de Tommaso M, Deus J, Domin M, Egorova-Brumley N, Elliott J, Fanton S, Fauchon C, Flor H, Franz CE, Gatt JM, Gerdhem P, Gilman JM, Gollub RL, Govind V, Graven-Nielsen T, Håkansson G, Hales T, Haswell C, Heukamp NJ, Hu L, Huang L, Hussain A, Jensen K, Kircher T, Kremen WS, Leehr EJ, Lindquist M, Loggia ML, Lotze M, Martucci KT, Meeker TJ, Meinert S, Millard SK, Morey RA, Murillo C, Nees F, Nenadic I, Park HRP, Peng X, Ploner M, Pujol J, Robayo LE, Salan T, Seminowicz DA, Serian A, Slater R, Stein F, Stevens J, Strauss S, Sun D, Vachon-Presseau E, Valdes-Hernandez PA, Vanneste S, Vernon M, Verriotis M, Wager TD, Widerstrom-Noga E, Woodbury A, Zeidan F, Bhatt RR, Ching CRK, Haddad E, Thomopoulos SI, Thompson PM, Gustin SM.  Pain. 2024 Dec 1;165(12):2662-2666. 

Prevalence and Correlates of Frailty Among Older People With and Without HIV in Rural Uganda.

Mbabazi P, Chen G, Ritchie CS, Tsai AC, Reynolds Z, Paul R, Seeley J, Tong Y, Hoeppner S, Okello S, Nakasujja N, Olivieri-Mui B, Tanner JA, Saylor D, Asiimwe S, Siedner MJ, Greene M.  J Acquir Immune Defic Syndr. 2024 Dec 1;97(4):402-408. 

Trajectories of posttraumatic stress symptoms following collective violence: A systematic review and meta-analyses.

Oppo A, Forresi B, Barbieri A, Koenen KC.  J Trauma Stress. 2024 Dec;37(6):837-849. 

Design of a multicenter randomized controlled trial of a post-discharge suicide prevention intervention for high-risk psychiatric inpatients: The Veterans Coordinated Community Care Study.

Weinstock LM, Bishop TM, Bauer MS, Benware J, Bossarte RM, Bradley J, Dobscha SK, Gibbs J, Gildea SM, Graves H, Haas G, House S, Kennedy CJ, Landes SJ, Liu H, Luedtke A, Marx BP, Miller A, Nock MK, Owen RR, Pigeon WR, Sampson NA, Santiago-Colon A, Shivakumar G, Urosevic S, Kessler RC.  Int J Methods Psychiatr Res. 2024 Dec;33(4):e70003. 

Identifying Genetically Inferred Effects Linking Posttraumatic Stress Disorder to Women’s Health, Lipid Disorders, and Malaria Medications.

Pathak GA, Wendt FR, Maihofer AX; Posttraumatic Stress Disorder Working Group of the Psychiatric Genomics Consortium; Ressler KJ, Stein MB, Koenen KC, Nievergelt CM, Polimanti R.

Am J Psychiatry. 2024 Dec 1;181(12):1127-1130. 

Diagnosing and Treating ADHD in Adults: Balancing Individual Benefits and Population Risks.

Blanco C, Surman CBH.  JAMA Psychiatry. 2024 Dec 1;81(12):1169-1170. 

The theoretical sensitivity of virtual assessment of catatonia.

Luccarelli J, Smith JR, Heckers S, Fricchione G, Wilson JE.  Schizophr Res. 2024 Dec;274:486-488. 

A qualitative exploration of the client-provider relationship and its role in discussing sexual health and HIV among African American women in the US South.

Vanderkruik R, Goodman GR, Blyler A, Ott C, Rivas A, Elopre L, Krakower D, Kudroff K, Wise J, Underwood E, McDonald V, Campbell M, Kempf MC, Psaros C.  Sex Reprod Healthc. 2024 Dec;42:101043. 

Heart rate variability wrist-wearable biomarkers identify adverse posttraumatic neuropsychiatric sequelae after traumatic stress exposure.

Guichard L, An X, Neylan TC, Clifford GD, Li Q, Ji Y, Macchio L, Baker J, Beaudoin FL, Jovanovic T, Linnstaedt SD, Germine LT, Bollen KA, Rauch SL, Haran JP, Storrow AB, Lewandowski C, Musey PI Jr, Hendry PL, Sheikh S, Jones CW, Punches BE, Swor RA, Gentile NT, Pascual JL, Seamon MJ, Datner EM, Pearson C, Peak DA, Merchant RC, Domeier RM, Rathlev NK, O’Neil BJ, Sergot P, Sanchez LD, Bruce SE, Sheridan JF, Harte SE, Ressler KJ, Koenen KC, Kessler RC, McLean SA; AURORA Study Group.  Psychiatry Res. 2024 Dec;342:116260.