The Mass General Department of Psychiatry encompasses more than 60 specialty integrated clinical and research programs. Our wide-ranging research portfolio spans clinical and basic research covering virtually every major psychiatric disorder, as well as the psychiatric consequences of medical illness.
These initiatives have led to notable expansions in genetics, neuroimaging and basic neuroscience, and this model of cross-talk between clinical care and science has consistently led to research advances that inform and advance clinical care.
Effect of cognitive behavioural therapy and yoga for generalised anxiety disorder on sleep quality in a randomised controlled trial: the role of worry, mindfulness, and perceived stress as mediators.
Jacoby RJ, Brown ML, Wieman ST, Rosenfield D, Hoeppner SS, Bui E, Hoge EA, Khalsa SBS, Hofmann SG, Simon NM. J Sleep Res. 2023 Aug 14.
Screening for post-traumatic stress disorder following childbirth using the Peritraumatic Distress Inventory.
Jagodnik KM, Ein-Dor T, Chan SJ, Ashkenazy AT, Bartal A, Barry RL, Dekel S. J Affect Disord. 2023 Dec 7;348:17-25.
Increasing the Repertoire for Depression Care: Methods and Challenges of a Randomized Controlled Trial of Peer Support for Vulnerable Older Adults.
Joo JH, Davey-Rothwell M, Choi N, Gallo J, Mace RA, Xie A. Am J Geriatr Psychiatry. 2023
Benzodiazepine Prescriptions for Homeless Veterans Affairs Service Users With Mental Illness.
Koh KA, Szymkowiak D, Tsai J. Psychiatr Serv. 2023 Oct 31:appips20220472.
Clinical harm reduction in substance use: An ethics-oriented primer and critique for hospital-based providers.
Kontos N, Rao V. J Eval Clin Pract. 2023 Nov 28.
Depressive symptoms and hippocampal volume in autosomal dominant Alzheimer’s disease.
Langella S, Lopera F, Baena A, Fox-Fuller JT, Munera D, Martinez JE, Giudicessi A, Vannini P, Hanseeuw BJ, Marshall GA, Quiroz YT, Gatchel JR. Alzheimers Dement. 2023 Oct 14.
Effects of a Mind-Body Program for Chronic Pain in Older versus Younger Adults.
LaRowe LR, Bakhshaie J, Vranceanu AM, Greenberg J. J Pain Res. 2023 Nov 15;16:3917-3924.
Cessations of consciousness in meditation: Advancing a scientific understanding of nirodha samāpatti.
Laukkonen RE, Sacchet MD, Barendregt H, Devaney KJ, Chowdhury A, Slagter HA. Prog Brain Res. 2023;280:61-87.
Mental imagery of suicide and non-suicidal self-injury: A meta-analysis and systematic review.
Lawrence HR, Balkind EG, Ji JL, Burke TA, Liu RT. Clin Psychol Rev. 2023 Jul;103:102302.
Impact of selection bias on polygenic risk score estimates in healthcare settings.
Lee YH, Thaweethai T, Sheu YH, Feng YA, Karlson EW, Ge T, Kraft P, Smoller JW. Psychol Med. 2023 Nov;53(15):7435-7445.
Early feasibility testing of a web-based mind-body resiliency program for adults with neurofibromatosis: The NF-Web study.
Lester EG, Fishbein NS, Peterson A, Vranceanu AM. PEC Innov. 2022 Aug 20;1:100076.
Intersectional approaches to risk, resilience, and mental health in marginalized populations: Introduction to the special section.
Liu RT, Anglin DM, Dyar C, Alvarez K. J Psychopathol Clin Sci. 2023 Jul;132(5):527-530.
Longitudinal Associations Between Cannabis Use and Cognitive Impairment in a Clinical Sample of Middle-Aged Adults Using Cannabis for Medical Symptoms.
Livne O, Potter KW, Schuster RM, Gilman JM. Cannabis Cannabinoid Res. 2023 Aug 25.
Brain microvascular endothelial cells and blood-brain barrier dysfunction in psychotic disorders.
Lizano P, Pong S, Santarriaga S, Bannai D, Karmacharya R. Mol Psychiatry. 2023 Sep;28(9):3698-3708.
Peer support interventions in patients with kidney failure: A systematic review.
Longley RM, Harnedy LE, Ghanime PM, Arroyo-Ariza D, Deary EC, Daskalakis E, Sadang KG, West J, Huffman JC, Celano CM, Amonoo HL. J Psychosom Res. 2023 Aug;171:111379.
Association between the timing of childhood adversity and epigenetic patterns across childhood and adolescence: findings from the Avon Longitudinal Study of Parents and Children (ALSPAC) prospective cohort.
Lussier AA, Zhu Y, Smith BJ, Cerutti J, Fisher J, Melton PE, Wood NM, Cohen-Woods S, Huang RC, Mitchell C, Schneper L, Notterman DA, Simpkin AJ, Smith ADAC, Suderman MJ, Walton E, Relton CL, Ressler KJ, Dunn EC. Lancet Child Adolesc Health. 2023 Aug;7(8):532-543.
Low-Level Laser Therapy for Acute Pain: A Comprehensive Review.
Lutfallah S, Wajid I, Sinnathamby ES, Maitski RJ, Edinoff AN, Shekoohi S, Cornett EM, Urman RD, Kaye AD. Curr Pain Headache Rep. 2023 Oct;27(10):607-613.
Accelerometry measures of physical activity and sedentary behavior: Associations with cognitive functioning in MS.
Manglani HR, Phansikar M, Duraney EJ, McKenna MR, Canter R, Nicholas JA, Andridge R, Prakash RS. Mult Scler Relat Disord. 2023 Nov;79:104963.
Alcohol Use Disorder Treatment in Sexually and Gender Diverse Patients: A Retrospective Cohort Study.
McDowell MJ, King DS, Gitin S, Miller AS, Batchelder AW, Busch AB, Greenfield SF, Huskamp HA, Keuroghlian AS. J Clin Psychiatry. 2023 Aug 28;84(5).
A Manualized Behavioral Therapy Intervention for Youth with Autism Spectrum Disorder and Substance Use Disorder.
McKowen J, Berger A, Towbin J, Yule AM, Woodward D, Nowinski L, Forchelli G, Meyers RJ, Joshi G, Wilens TE. Case Rep Psychiatry. 2023 Apr 1;2023:8998160.
How do experts in psychiatric genetics view the clinical utility of polygenic risk scores for schizophrenia?
Moorthy T, Nguyen H, Chen Y, Austin J, Smoller JW, Hercher L, Sabatello M. Am J Med Genet B Neuropsychiatr Genet. 2023 Oct-Dec;192(7-8):161-170.
The APOE-R136S mutation protects against APOE4-driven Tau pathology, neurodegeneration and neuroinflammation.
Nelson MR, Liu P, Agrawal A, Yip O, Blumenfeld J, Traglia M, Kim MJ, Koutsodendris N, Rao A, Grone B, Hao Y, Yoon SY, Xu Q, De Leon S, Choenyi T, Thomas R, Lopera F, Quiroz YT, Arboleda-Velasquez JF, Reiman EM, Mahley RW, Huang Y. Nat Neurosci. 2023 Dec;26(12):2104-2121.
NRX-101 (D-cycloserine plus lurasidone) vs. lurasidone for the maintenance of initial stabilization after ketamine in patients with severe bipolar depression with acute suicidal ideation and behavior: a randomized prospective phase 2 trial.
Nierenberg A, Lavin P, Javitt DC, Shelton R, Sapko MT, Mathew S, Besthof RE, Javitt JC. Int J Bipolar Disord. 2023 Aug 13;11(1):28.
Individuals with depression exhibiting a pro-inflammatory phenotype receiving omega-3 polyunsaturated fatty acids experience improved motivation-related cognitive function: Preliminary results from a randomized controlled trial.
Mac Giollabhui N, Mischoulon D, Dunlop BW, Kinkead B, Schettler PJ, Liu RT, Okereke OI, Lamon-Fava S, Fava M, Rapaport MH. Brain, Behavior, & Immunity – Health. 2023 Jul 7.
Human stem cell-based models to study synaptic dysfunction and cognition in schizophrenia: A narrative review.
Santarriaga S, Gerlovin K, Layadi Y, Karmacharya R. Schizophr Res. 2023 Mar 14. pii: S0920-9964(23)00084-1.
