Roy Perlis, MD, MSc is the Director of the Center for Quantitative Health at MGH and Associate Chief for Research in the Department of Psychiatry. He is the Ronald I. Dozoretz, MD Endowed Professor of Psychiatry at Harvard Medical School and Associate Editor (Neuroscience) at JAMA's new open-access journal, JAMA Network - Open. His research is focused on identifying predictors of treatment response in brain diseases, and using these biomarkers to develop novel treatments. He directs two complementary laboratory efforts, one focused on patient-derived cellular models and one applying machine learning to large clinical databases.