A new study indicates that higher doses of the omega-3 fatty acid eicosapentaenoic acid may alleviate depressive symptoms in overweight individuals with elevated inflammatory markers.

Nearly half of these real-world patients with treatment-resistant depression elected to continue with IV ketamine because of perceived improvement of their depression and suicidal ideation. 

Adjunctive testosterone was no more effective than placebo in improving symptoms of depression, fatigue, or sexual dysfunction in women with antidepressant-resistant MDD.

Augmentation with an oral analogue of allopregnanolone resulted in remission in menopausal women who failed antidepressant treatment.