New Publications from the Mass General Department of Psychiatry – June 21, 2024

The Mass General Department of Psychiatry encompasses more than 60 specialty integrated clinical and research programs.  Our wide-ranging research portfolio spans clinical and basic research covering virtually every major psychiatric disorder, as well as the psychiatric consequences of medical illness. 

These initiatives have led to notable expansions in genetics, neuroimaging and basic neuroscience, and this model of cross-talk between clinical care and science has consistently led to research advances that inform and advance clinical care.

Prospective Relations between Life Stress, Emotional Clarity, and Suicidal Ideation in an Adolescent Clinical Sample.

López R Jr, Turnamian MR, Liu RT.  J Clin Child Adolesc Psychol. 2024 May 1:1-14. 

Genome-wide association analyses identify 95 risk loci and provide insights into the neurobiology of post-traumatic stress disorder.

Nievergelt CM, Maihofer AX, Atkinson EG, Chen CY, Choi KW, Coleman JRI, Daskalakis NP, Duncan LE, Polimanti R, Aaronson C, Amstadter AB, Andersen SB, Andreassen OA, Arbisi PA, Ashley-Koch AE, Austin SB, Avdibegoviç E, Babić D, Bacanu SA, Baker DG, Batzler A, Beckham JC, Belangero S, Benjet C, Bergner C, Bierer LM, Biernacka JM, Bierut LJ, Bisson JI, Boks MP, Bolger EA, Brandolino A, Breen G, Bressan RA, Bryant RA, Bustamante AC, Bybjerg-Grauholm J, Bækvad-Hansen M, Børglum AD, Børte S, Cahn L, Calabrese JR, Caldas-de-Almeida JM, Chatzinakos C, Cheema S, Clouston SAP, Colodro-Conde L, Coombes BJ, Cruz-Fuentes CS, Dale AM, Dalvie S, Davis LK, Deckert J, Delahanty DL, Dennis MF, Desarnaud F, DiPietro CP, Disner SG, Docherty AR, Domschke K, Dyb G, Kulenović AD, Edenberg HJ, Evans A, Fabbri C, Fani N, Farrer LA, Feder A, Feeny NC, Flory JD, Forbes D, Franz CE, Galea S, Garrett ME, Gelaye B, Gelernter J, Geuze E, Gillespie CF, Goleva SB, Gordon SD, Goçi A, Grasser LR, Guindalini C, Haas M, Hagenaars S, Hauser MA, Heath AC, Hemmings SMJ, Hesselbrock V, Hickie IB, Hogan K, Hougaard DM, Huang H, Huckins LM, Hveem K, Jakovljević M, Javanbakht A, Jenkins GD, Johnson J, Jones I, Jovanovic T, …

See abstract for full author list ➔  Nat Genet. 2024 May;56(5):792-808. 

Effect of Stress-Related Neural Pathways on the Cardiovascular Benefit of Physical Activity.

Zureigat H, Osborne MT, Abohashem S, Mezue K, Gharios C, Grewal S, Cardeiro A, Naddaf N, Civieri G, Abbasi T, Radfar A, Aldosoky W, Seligowski AV, Wasfy MM, Guseh JS, Churchill TW, Rosovsky RP, Fayad Z, Rosenzweig A, Baggish A, Pitman RK, Choi KW, Smoller J, Shin LM, Tawakol A.  J Am Coll Cardiol. 2024 Apr 23;83(16):1543-1553. 

Longitudinal Measurement Invariance of the ASEBA Youth/Adult Self-Reports Across the Transition From Adolescence to Adulthood.

Moriarity DP, Mac Giollabhui N, Cardoso Melo D, Hartman C.  Assessment. 2024 Apr 18:10731911241245875. 

Polygenic risk for suicide attempt is associated with lifetime suicide attempt in US soldiers independent of parental risk.

Stein MB, Jain S, Papini S, Campbell-Sills L, Choi KW, Martis B, Sun X, He F, Ware EB, Naifeh JA, Aliaga PA, Ge T; for International Suicide Genetics Consortium; for MVP Suicide Exemplar Workgroup; for VA Million Veteran Program; for Suicide Working Group of the Psychiatric Genomics Consortium; Smoller JW, Gelernter J, Kessler RC, Ursano RJ.  J Affect Disord. 2024 Apr 15;351:671-682. 

Family dementia caregivers with suicidal ideation improve with mentalizing imagery therapy: Results from a pilot study.

Madarasmi S, Gutierrez-Ramirez P, Barsoum N, Banerjee S, Ramirez Gomez L, Melero-Dominguez M, Gitlin LN, Pederson A, Liu RT, Jain FA.  J Affect Disord Rep. 2024 Apr;16:100721. 

Effects of genetically predicted posttraumatic stress disorder on autoimmune phenotypes.

Maihofer AX, Ratanatharathorn A, Hemmings SMJ, Costenbader KH, Michopoulos V, Polimanti R, Rothbaum AO, Seedat S, Mikita EA; CHARGE Inflammation Working Group; Psychiatric Genomics Consortium PTSD Working Group; Smith AK, Salem RM, Shaffer RA, Wu T, Sebat J, Ressler KJ, Stein MB, Koenen KC, Wolf EJ, Sumner JA, Nievergelt CM.  Transl Psychiatry. 2024 Apr 1;14(1):172. 

Childhood maltreatment and health in the UK Biobank: triangulation of outcome-wide and polygenic risk score analyses.

Espinosa Dice AL, Lawn RB, Ratanatharathorn A, Roberts AL, Denckla CA, Kim AH, de la Rosa PA, Zhu Y, VanderWeele TJ, Koenen KC. BMC Med. 2024 Mar 25;22(1):135. 

Sex Differences in Response Inhibition-Related Neural Predictors of Posttraumatic Stress Disorder in Civilians With Recent Trauma.

Borst B, Jovanovic T, House SL, Bruce SE, Harnett NG, Roeckner AR, Ely TD, Lebois LAM, Young D, Beaudoin FL, An X, Neylan TC, Clifford GD, Linnstaedt SD, Germine LT, Bollen KA, Rauch SL, Haran JP, Storrow AB, Lewandowski C, Musey PI Jr, Hendry PL, Sheikh S, Jones CW, Punches BE, Hudak LA, Pascual JL, Seamon MJ, Datner EM, Pearson C, Peak DA, Domeier RM, Rathlev NK, O’Neil BJ, Sergot P, Sanchez LD, Harte SE, Koenen KC, Kessler RC, McLean SA, Ressler KJ, Stevens JS, van Rooij SJH.  Biol Psychiatry Cogn Neurosci Neuroimaging. 2024 Mar 22:S2451-9022(24)00080-6. 

Post-traumatic stress disorder in a national sample of preadolescent children 9 to 10 years old: Prevalence, correlates, clinical sequelae, and treatment utilization.

Levin RY, Liu RT.  Transl Psychiatry. 2024 Mar 19;14(1):152. 

Association of neurotransmitter pathway polygenic risk with specific symptom profiles in psychosis.

Warren TL, Tubbs JD, Lesh TA, Corona MB, Pakzad SS, Albuquerque MD, Singh P, Zarubin V, Morse SJ, Sham PC, Carter CS, Nord AS.  Mol Psychiatry. 2024 Mar 15. 

Post-traumatic stress and future substance use outcomes: leveraging antecedent factors to stratify risk.

Garrison-Desany HM, Meyers JL, Linnstaedt SD, House SL, Beaudoin FL, An X, Zeng D, Neylan TC, Clifford GD, Jovanovic T, Germine LT, Bollen KA, Rauch SL, Haran JP, Storrow AB, Lewandowski C, Musey PI Jr, Hendry PL, Sheikh S, Jones CW, Punches BE, Swor RA, Gentile NT, Hudak LA, Pascual JL, Seamon MJ, Harris E, Pearson C, Peak DA, Domeier RM, Rathlev NK, O’Neil BJ, Sergot P, Sanchez LD, Bruce SE, Joormann J, Harte SE, McLean SA, Koenen KC, Denckla CA.  Front Psychiatry. 2024 Mar 8;15:1249382. 

The Role of Psychiatry for Transgender and Gender Diverse Adults.

Beazer M, Breiger M, Keuroghlian AS.  Harv Rev Psychiatry. 2024 Mar-Apr 01;32(2):58-62. 

Social and circadian rhythm dysregulation and suicide: A systematic review and meta-analysis.

Walsh RFL, Maddox MA, Smith LT, Liu RT, Alloy LB.  Neurosci Biobehav Rev. 2024 Mar;158:105560. 

Disclosures of self-injurious thoughts and behaviors to parents in the context of adolescent therapy: A qualitative investigation.

Bettis AH, Burke TA, Scott SR, Bedock C, Ambriano C, Parrish J, Marsh D, Fox KR.  J Clin Psychol. 2024 Mar;80(3):537-558.